474432-65-0
474432-65-0
Chemical Structure
FAUC 346
- CAS No.: 474432-65-0
- Formula:C24H29N3O2S
- Molecular Weight:423.57
IUPAC Name: N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide
InChIKey: KFMBPIZMZUDONQ-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=CC=CC=C2S1)NCCCCN3CCN(C4=CC=CC=C4OC)CC3
Biological Activity: FAUC 346, a highly selective D3 partial agonist (EC50 = 1.5 nM)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FAUC 346 | 99.90% | FAUC 346, a highly selective D3 partial agonist (EC50 = 1.5 nM). | ||||||||||||||||||||
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References
- [1]. Bertrand Kuhnast, et al. Synthesis and radiolabeling of N-[4-[4-(2-[11C]methoxyphenyl)piperazin-1-yl]butyl]benzo[b]thiophene-2-carboxamide -- a potential radiotracer for D3 receptor imaging with PET. Nucl Med Biol. 2006 Aug;33(6):785-95. [Content Brief]
- [2]. Carsten Hocke, et al. 18F-Labeled FAUC 346 and BP 897 derivatives as subtype-selective potential PET radioligands for the dopamine D3 receptor. ChemMedChem. 2008 May;3(5):788-93. [Content Brief]
