491871-58-0
491871-58-0
Chemical Structure
TCS PIM-1 1
Synonym(s): SC 204330
- CAS No.: 491871-58-0
- Formula:C18H11BrN2O2
- Molecular Weight:367.20
IUPAC Name: 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile
InChIKey: SVSYJTYGPLVUOZ-UHFFFAOYSA-N
SMILES: OC1=C(C(N2)=CC(C3=CC=CC=C3)=C(C#N)C2=O)C=C(Br)C=C1
Biological Activity: TCS PIM-1 1 (SC 204330) is a potent, selective and ATP-competitive Pim-1 kianse inhibitor with an IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2 (IC50s >20000 nM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TCS PIM-1 1 | 98.40% | TCS PIM-1 1 (SC 204330) is a potent, selective and ATP-competitive Pim-1 kianse inhibitor with an IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2 (IC50s >20000 nM). | ||||||||||||||||||||
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References
Keywords
