499231-24-2
499231-24-2
Chemical Structure
Cyclopyrimorate
- CAS No.: 499231-24-2
- Formula:C19H20ClN3O4
- Molecular Weight:389.83
IUPAC Name: 6-chloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazin-4-yl morpholine-4-carboxylate
InChIKey: BXIGJZDQFDFASM-UHFFFAOYSA-N
SMILES: O=C(OC1=CC(Cl)=NN=C1OC2=C(C=CC=C2C3CC3)C)N4CCOCC4
Biological Activity: Cyclopyrimorate, a highly effective bleaching herbicide for weed control in rice fields, targets homogentisate solanesyltransferase (HST). HST is a downstream enzyme of 4-hydroxyphenylpyruvate dioxygenase in the plastoquinone (PQ) biosynthesis pathway[1][2].
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Cyclopyrimorate | 99.44% | Cyclopyrimorate, a highly effective bleaching herbicide for weed control in rice fields, targets homogentisate solanesyltransferase (HST). HST is a downstream enzyme of 4-hydroxyphenylpyruvate dioxygenase in the plastoquinone (PQ) biosynthesis pathway. | ||||||||||||||||||||
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Structural Analogs
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HY-146353HIV-1 inhibitor-29 -
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HY-185177Antifungal agent 156 -
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HY-B1316Trimetozine -
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HY-11100Asenapine maleate -
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HY-149698Tyrosinase-IN-17 -
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HY-147684FGFR-IN-7 -
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HY-106935ACGP 29030A -
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HY-173162GPV0057 -
Similarity Score 0.39
HY-120395UC-514321 -
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References
- [1]. Shino M, et al. In vivo and in vitro evidence for the inhibition of homogentisate solanesyltransferase by cyclopyrimorate. Pest Manag Sci. 2019 Nov 27. [Content Brief]
- [2]. Shino M, et al. Action mechanism of bleaching herbicide cyclopyrimorate, a novel homogentisate solanesyltransferase inhibitor. J Pestic Sci. 2018 Nov 20;43(4):233-239. [Content Brief]
