500733-49-3
Chemical Structure
Rapamycin dialdehyde
- CAS No.: 500733-49-3
- Formula:C51H79NO15
- Molecular Weight:946.17
IUPAC Name: (2R,3S,6R,7E,9R,10R,12R,14S,15E)-9-hydroxy-1-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-10-methoxy-2,6,8,12,14-pentamethyl-5,11,17-trioxoheptadeca-7,15-dien-3-yl (S)-1-(2-((2R,3R,6S)-2-hydroxy-6-((S,E)-2-methoxy-3-methyl-5-oxopent-3-en-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate
InChIKey: SQLZDXFTEMMIKN-SMOTWFINSA-N
SMILES: O=C([C@@]1(O[C@@H](CC[C@H]1C)C[C@H](OC)/C(C)=C/C=O)O)C(N2[C@@H](CCCC2)C(O[C@@H](CC([C@H](C)/C=C(C)/[C@@H](O)[C@@H](OC)C([C@H](C)C[C@H](C)/C=C/C=O)=O)=O)[C@H](C)C[C@H]3C[C@H]([C@@H](CC3)O)OC)=O)=O
Biological Activity: Rapamycin dialdehyde is a non-immunosuppressive macrolide dialdehyde that promotes neuronal regeneration and functional recovery by inducing neurite outgrowth, and inhibits solid tumor cell growth and hyperproliferative vascular diseases. Rapamycin dialdehyde is used in the research of neurodegenerative diseases and cancer[1][2].
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Rapamycin dialdehyde | Rapamycin dialdehyde is a non-immunosuppressive macrolide dialdehyde that promotes neuronal regeneration and functional recovery by inducing neurite outgrowth, and inhibits solid tumor cell growth and hyperproliferative vascular diseases. Rapamycin dialdehyde is used in the research of neurodegenerative diseases and cancer. | |||||||||||||||||||||
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