50335-55-2
50335-55-2
Chemical Structure
Mezilamine
- CAS No.: 50335-55-2
- Formula:C11H18ClN5S
- Molecular Weight:287.81
IUPAC Name: 4-chloro-N-methyl-6-(4-methylpiperazin-1-yl)-5-(methylthio)pyrimidin-2-amine
InChIKey: ITYXRJDDBZMFAY-UHFFFAOYSA-N
SMILES: CSC1=C(N2CCN(C)CC2)N=C(NC)N=C1Cl
Biological Activity: Mezilamine is a potent antidopaminergic agent. Mezilamine induces a concentration dependent increase in the electrically stimulated overflow of 3H-noradrenaline from rat cortical slices, without affecting the basal overflow. Mezilamine acts as a presynaptic α-adrenoceptor antagonist and a postsynaptic α-adrenoceptor agonist[1].
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Mezilamine | Mezilamine is a potent antidopaminergic agent. Mezilamine induces a concentration dependent increase in the electrically stimulated overflow of 3H-noradrenaline from rat cortical slices, without affecting the basal overflow. Mezilamine acts as a presynaptic α-adrenoceptor antagonist and a postsynaptic α-adrenoceptor agonist. | |||||||||||||||||||||
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