513-00-8
513-00-8
Chemical Structure
Iso-OMPA
Synonym(s): Tetraisopropyl pyrophosphoramide
- CAS No.: 513-00-8
- Formula:C12H32N4O3P2
- Molecular Weight:342.36
InChIKey: IOIMDJXKIMCMIG-UHFFFAOYSA-N
SMILES: O=P(NC(C)C)(NC(C)C)OP(NC(C)C)(NC(C)C)=O
Biological Activity: Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE)[1][2][3].
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Iso-OMPA | 99.9% | Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE). | ||||||||||||||||||||
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Iso-OMPA (Standard) | ≥98% | Iso-OMPA (Standard) is the analytical standard of Iso-OMPA. This product is intended for research and analytical applications. Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE). | ||||||||||||||||||||
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References
- [1]. Rodríguez-Fuentes G, et al. Characterization of cholinesterase activity from different tissues of Nile tilapia (Oreochromis niloticus). Mar Environ Res. 2004 Aug-Dec;58(2-5):505-9. [Content Brief]
- [2]. X Norel, et al. Degradation of acetylcholine in human airways: role of butyrylcholinesterase. Br J Pharmacol. 1993 Apr;108(4):914-9. [Content Brief]
- [3]. Z Grubic, et al. Iso-OMPA-induced potentiation of soman toxicity in rat correlates with the inhibition of plasma carboxylesterases. Arch Toxicol. 1988;62(5):398-9. [Content Brief]
