513-00-8
513-00-8
Chemical Structure
Iso-OMPA
Synonym(s): Tetraisopropyl pyrophosphoramide
- CAS No.: 513-00-8
- Formula:C12H32N4O3P2
- Molecular Weight:342.36
InChIKey: IOIMDJXKIMCMIG-UHFFFAOYSA-N
SMILES: O=P(NC(C)C)(NC(C)C)OP(NC(C)C)(NC(C)C)=O
Biological Activity: Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE)[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Iso-OMPA | 99.9% | Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Iso-OMPA (Standard) | ≥98% | Iso-OMPA (Standard) is the analytical standard of Iso-OMPA. This product is intended for research and analytical applications. Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.55
HY-N7819Pristane -
Similarity Score 0.55
HY-W7168892,6,10,14-Tetramethylhexadecane -
Similarity Score 0.54
HY-141323C2-Bis-phosphoramidic acid diethyl ester -
Similarity Score 0.54
HY-W144704(rac)-Dihydrophytol -
Similarity Score 0.54
HY-W144704B(3RS,7R,11R)-Dihydrophytol -
Similarity Score 0.53
HY-114577Palifosfamide tromethamine -
Similarity Score 0.53
HY-W7207583,7,11-Trimethyl-1-dodecanol -
Similarity Score 0.52
HY-13610AN1,N11-Diethylnorspermine tetrahydrochloride -
Similarity Score 0.52
HY-13610BN1,N11-Diethylnorspermine hydrobromide -
Explore the MedChemAI to find more analogs
References
- [1]. Rodríguez-Fuentes G, et al. Characterization of cholinesterase activity from different tissues of Nile tilapia (Oreochromis niloticus). Mar Environ Res. 2004 Aug-Dec;58(2-5):505-9. [Content Brief]
- [2]. X Norel, et al. Degradation of acetylcholine in human airways: role of butyrylcholinesterase. Br J Pharmacol. 1993 Apr;108(4):914-9. [Content Brief]
- [3]. Z Grubic, et al. Iso-OMPA-induced potentiation of soman toxicity in rat correlates with the inhibition of plasma carboxylesterases. Arch Toxicol. 1988;62(5):398-9. [Content Brief]
