51596-11-3
51596-11-3
Chemical Structure
Milbemycin A4
- CAS No.: 51596-11-3
- Formula:C32H46O7
- Molecular Weight:542.70
InChIKey: VOZIAWLUULBIPN-LRBNAKOISA-N
SMILES: O=C1[C@]2([H])C=C(C)[C@@H](O)[C@]3([H])[C@@]2(O)/C(CO3)=C/C=C/[C@H](C)C/C(C)=C/C[C@]4([H])C[C@@](O1)([H])C[C@@]5(O[C@H](CC)[C@@H](C)CC5)O4
Biological Activity: Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity[1][2].
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Milbemycin A4 | 99.13% | Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity. | ||||||||||||||||||||
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Milbemycin A4 (Standard) | ≥98% | Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity. | ||||||||||||||||||||
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References
- [1]. Li J, et al. Isolation and identification of new macrocyclic lactones from a genetically engineered strain Streptomyces bingchenggensis BCJ60. J Antibiot (Tokyo). 2017 Mar;70(3):297-300. [Content Brief]
- [2]. Takiguchi Y, et al. Milbemycins, a new family of macrolide antibiotics: fermentation, isolation and physico-chemical properties. J Antibiot (Tokyo). 1980 Oct;33(10):1120-7. [Content Brief]
