52179-44-9
52179-44-9
Chemical Structure
Graphislactone A
- CAS No.: 52179-44-9
- Formula:C16H14O6
- Molecular Weight:302.28
IUPAC Name: 4,7-dihydroxy-3,9-dimethoxy-1-methyl-6H-benzo[c]chromen-6-one
InChIKey: SMKUDZVEVLDBSV-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C(OC)=CC(C)=C2C3=CC(OC)=CC(O)=C13)O
Biological Activity: Graphislactone A is an antioxidant, which is found in Cephalosporium IFB-E001 and M. olivacea. Graphislactone A inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM. Graphislactone A is promising for research of oxidative damage-initiated diseases[1][2].
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Graphislactone A | Graphislactone A is an antioxidant, which is found in Cephalosporium IFB-E001 and M. olivacea. Graphislactone A inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM. Graphislactone A is promising for research of oxidative damage-initiated diseases. | |||||||||||||||||||||
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References
- [1]. Song YC, et al. Characterization of graphislactone A as the antioxidant and free radical-scavenging substance from the culture of Cephalosporium sp. IFB-E001, an endophytic fungus in Trachelospermum jasminoides. Biol Pharm Bull. 2005 Mar;28(3):506-9. [Content Brief]
- [2]. Hormazabal E, et al. Metabolites from Microsphaeropsis olivacea, an endophytic fungus of Pilgerodendron uviferum. Z Naturforsch C J Biosci. 2005 Jan-Feb;60(1-2):11-21. [Content Brief]
