52510-53-9
52510-53-9
Chemical Structure
Tetranor-PGAM
- CAS No.: 52510-53-9
- Formula:C16H22O6
- Molecular Weight:310.34
IUPAC Name: 8-((1S,5R)-5-(2-carboxyethyl)-4-oxocyclopent-2-en-1-yl)-6-oxooctanoic acid
InChIKey: HYPIFMOQVFWSBF-WCQYABFASA-N
SMILES: OC(CC[C@@H]1[C@H](C=CC1=O)CCC(CCCCC(O)=O)=O)=O
Biological Activity: Tetranor-PGAM is a tetranor-prostaglandin A metabolite. Tetranor-PGAM is a dehydration product of tetranor-PGEM (HY-114988). Tetranor-PGAM can be measured as a surrogate for tetranor-PGEM levels in urine[1][2].
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Tetranor-PGAM | Tetranor-PGAM is a tetranor-prostaglandin A metabolite. Tetranor-PGAM is a dehydration product of tetranor-PGEM (HY-114988). Tetranor-PGAM can be measured as a surrogate for tetranor-PGEM levels in urine. | |||||||||||||||||||||
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References
- [1]. Gregory W. Endres, et al. Methods for manufacturing tetranor-prostaglandin d, j, e, a and f metabolites. Patent, WO2011159740A2.
- [2]. Neale JR, et al. Liquid chromatography-tandem mass spectrometric quantification of the dehydration product of tetranor PGE-M, the major urinary metabolite of prostaglandin E(2) in human urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Aug 1;871(1):72-7. [Content Brief]
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