52549-17-4
52549-17-4
Chemical Structure
Pranoprofen
- CAS No.: 52549-17-4
- Formula:C15H13NO3
- Molecular Weight:255.27
IUPAC Name: 2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid
InChIKey: TVQZAMVBTVNYLA-UHFFFAOYSA-N
SMILES: CC(C(O)=O)C1=CC2=C(C=C1)OC3=NC=CC=C3C2
Biological Activity: Pranoprofen is a non-steroidal anti-inflammatory agent (NSAID) for the research of keratitis or other ophthalmology diseases. Pranoprofen inhibit COX-1 and COX-2 enzymes, thus blocking arachidonic acid converted to eicosanoids and reducing prostaglandins synthesis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pranoprofen | 98.56% | Pranoprofen is a non-steroidal anti-inflammatory agent (NSAID) for the research of keratitis or other ophthalmology diseases. Pranoprofen inhibit COX-1 and COX-2 enzymes, thus blocking arachidonic acid converted to eicosanoids and reducing prostaglandins synthesis. | ||||||||||||||||||||
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Pranoprofen (Standard) | ≥98% | Pranoprofen (Standard) is the analytical standard of Pranoprofen. This product is intended for research and analytical applications. Pranoprofen is a non-steroidal anti-inflammatory agent (NSAID) for the research of keratitis or other ophthalmology diseases. Pranoprofen inhibit COX-1 and COX-2 enzymes, thus blocking arachidonic acid converted to eicosanoids and reducing prostaglandins synthesis. | ||||||||||||||||||||
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Pranoprofen-13C-d3 | Pranoprofen-13C-d3 (Pyaopofe-13C-d3) is 13C and deuterium labeled Pranoprofen. | |||||||||||||||||||||
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References
- [1]. Toru Hosoi, et al. Effect of pranoprofen on endoplasmic reticulum stress in the primary cultured glial cells. Neurochem Int. 2009 Jan;54(1):1-6. [Content Brief]
- [2]. Minting Chen, et al. The Therapeutic Effects and Possible Mechanism of Pranoprofen in Mouse Model of Corneal Alkali Burns. J Ophthalmol. 2020 Apr 6;2020:7485912. [Content Brief]
