53277-26-2
53277-26-2
Chemical Structure
2'-Nitroflavone
- CAS No.: 53277-26-2
- Formula:C15H9NO4
- Molecular Weight:267.24
InChIKey: CLWQBDUHBCAEBV-UHFFFAOYSA-N
SMILES: O=C1C2=CC=CC=C2OC(C3=C([N+]([O-])=O)C=CC=C3)=C1
Biological Activity: 2'-Nitroflavone is a PARP1 inhibitor. 2'-Nitroflavone inhibits the proliferation, induces cell cycle arrest and apoptosis of triple-negative breast cancer cells. 2'-Nitroflavone also inhibits the migration of triple-negative breast cancer cells and endothelial cells. 2'-Nitroflavone exhibits antitumor activity and can be used in the research of tumors such as triple-negative breast cancer[1].
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2'-Nitroflavone | 2'-Nitroflavone is a PARP1 inhibitor. 2'-Nitroflavone inhibits the proliferation, induces cell cycle arrest and apoptosis of triple-negative breast cancer cells. 2'-Nitroflavone also inhibits the migration of triple-negative breast cancer cells and endothelial cells. 2'-Nitroflavone exhibits antitumor activity and can be used in the research of tumors such as triple-negative breast cancer. | |||||||||||||||||||||
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