53472-37-0
Chemical Structure
Laricitrin
- CAS No.: 53472-37-0
- Formula:C16H12O8
- Molecular Weight:332.26
IUPAC Name: 2-(3,4-dihydroxy-5-methoxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
InChIKey: CFYMYCCYMJIYAB-UHFFFAOYSA-N
SMILES: O=C1C(O)=C(C2=CC(OC)=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13
Biological Activity: Laricitrin is a natural product with multiple biological activities. Laricitrin inhibits the phosphorylation and DNA-binding activity of STAT3, and downregulates the expression of IL-10. Laricitrin acts as an immunomodulator to regulate the differentiation, maturation and function of dendritic cells (DCs). Laricitrin inhibits the migration and invasion of lung cancer cells, and ameliorates lung cancer progression. Laricitrin can be used in research related to hypertension and lung cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Laricitrin | 99.36% | Laricitrin is a natural product with multiple biological activities. Laricitrin inhibits the phosphorylation and DNA-binding activity of STAT3, and downregulates the expression of IL-10. Laricitrin acts as an immunomodulator to regulate the differentiation, maturation and function of dendritic cells (DCs). Laricitrin inhibits the migration and invasion of lung cancer cells, and ameliorates lung cancer progression. Laricitrin can be used in research related to hypertension and lung cancer. | ||||||||||||||||||||
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- [1]. Chang WA, et al. Laricitrin ameliorates lung cancer-mediated dendritic cell suppression by inhibiting signal transducer and activator of transcription 3. Oncotarget. 2016 Dec 20;7(51):85220-85234. [Content Brief]
- [2]. Chang WA, et al. Laricitrin suppresses increased benzo(a)pyrene-induced lung tumor-associated monocyte-derived dendritic cell cancer progression. Oncology letters. 2016 Mar;11(3):1783-1790. [Content Brief]
Keywords
