54676-54-9
54676-54-9
Chemical Structure
(Z)-p-cyano-α-Cyanostilbene
- CAS No.: 54676-54-9
- Formula:C16H10N2
- Molecular Weight:230.26
IUPAC Name: (Z)-4-(1-cyano-2-phenylvinyl)benzonitrile
InChIKey: XDDAUUXKEGNGIY-MHWRWJLKSA-N
SMILES: N#C/C(C1=CC=C(C=C1)C#N)=C\C2=CC=CC=C2
Biological Activity: (Z)-p-cyano-α-Cyanostilbene (compound 11), a phenantrene derivative, has antiproliferative activity. (Z)-p-cyano-α-Cyanostilbene shows significant selectivity against HeLa (IC50=0.21 µM) and HepG2 (IC50=0.230 µM) cells without cytotoxic against normal skin fibroblasts (IC50>100 µM)[1].
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(Z)-p-cyano-α-Cyanostilbene | (Z)-p-cyano-α-Cyanostilbene (compound 11), a phenantrene derivative, has antiproliferative activity. (Z)-p-cyano-α-Cyanostilbene shows significant selectivity against HeLa (IC50=0.21 µM) and HepG2 (IC50=0.230 µM) cells without cytotoxic against normal skin fibroblasts (IC50>100 µM). | |||||||||||||||||||||
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