55778-02-4
55778-02-4
Chemical Structure
WZ811
- CAS No.: 55778-02-4
- Formula:C18H18N4
- Molecular Weight:290.36
IUPAC Name: N,N'-(1,4-phenylenebis(methylene))bis(pyridin-2-amine)
InChIKey: KBVFRXIGQQRMEF-UHFFFAOYSA-N
SMILES: C1(CNC2=NC=CC=C2)=CC=C(CNC3=NC=CC=C3)C=C1
Biological Activity: WZ811 is an orally active, highly potent competitive antagonist of CXCR4. WZ811 efficiently inhibits CXCR4/SDF-1 (or CXCL12)-mediated modulation of cAMP levels (EC50=1.2 nM) and SDF-1 induced Matrigel invasion in cells (EC50=5.2 nM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WZ811 | 99.80% | WZ811 is an orally active, highly potent competitive antagonist of CXCR4. WZ811 efficiently inhibits CXCR4/SDF-1 (or CXCL12)-mediated modulation of cAMP levels (EC50=1.2 nM) and SDF-1 induced Matrigel invasion in cells (EC50=5.2 nM). | ||||||||||||||||||||
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References
Keywords
