hRIO2 kinase ligand-1

Cat. No.: HY-156793 Purity: 99.95%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

hRIO2 kinase ligand-1 (com 9) is a ligand of hRIO2 kinase, with a Kd value of 520 nM.

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hRIO2 kinase ligand-1 Chemical Structure

CAS No. : 923841-73-0

Size	Price	Stock	Quantity
5 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 230	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 460	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 730	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

hRIO2 kinase ligand-1 (com 9) is a ligand of hRIO2 kinase, with a Kd value of 520 nM^[1].

Molecular Weight

262.31

Formula

C₁₇H₁₄N₂O

CAS No.

923841-73-0

Appearance

Solid

Color

White to off-white

SMILES

O=C(CC1=CC2=C(C=CC=C2)C=C1)NC3=NC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (381.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.8123 mL	19.0614 mL	38.1228 mL
5 mM	0.7625 mL	3.8123 mL	7.6246 mL
10 mM	0.3812 mL	1.9061 mL	3.8123 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.95%

Select Batch:

Data Sheet (267 KB) SDS (251 KB)

COA (246 KB) HNMR (236 KB) LCMS (91 KB)

Handling Instructions (2659 KB)

References

[1]. Varin T, et al. Discovery of selective RIO2 kinase small molecule ligand. Biochim Biophys Acta. 2015 Oct;1854(10 Pt B):1630-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.8123 mL	19.0614 mL	38.1228 mL	95.3071 mL
	5 mM	0.7625 mL	3.8123 mL	7.6246 mL	19.0614 mL
	10 mM	0.3812 mL	1.9061 mL	3.8123 mL	9.5307 mL
	15 mM	0.2542 mL	1.2708 mL	2.5415 mL	6.3538 mL
	20 mM	0.1906 mL	0.9531 mL	1.9061 mL	4.7654 mL
	25 mM	0.1525 mL	0.7625 mL	1.5249 mL	3.8123 mL
	30 mM	0.1271 mL	0.6354 mL	1.2708 mL	3.1769 mL
	40 mM	0.0953 mL	0.4765 mL	0.9531 mL	2.3827 mL
	50 mM	0.0762 mL	0.3812 mL	0.7625 mL	1.9061 mL
	60 mM	0.0635 mL	0.3177 mL	0.6354 mL	1.5885 mL
	80 mM	0.0477 mL	0.2383 mL	0.4765 mL	1.1913 mL
	100 mM	0.0381 mL	0.1906 mL	0.3812 mL	0.9531 mL