56187-47-4
56187-47-4
Chemical Structure
Cefazedone
Synonym(s): Refosporen
- CAS No.: 56187-47-4
- Formula:C18H15Cl2N5O5S3
- Molecular Weight:548.44
IUPAC Name: (6R,7R)-7-(2-(3,5-dichloro-4-oxopyridin-1(4H)-yl)acetamido)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: VTLCNEGVSVJLDN-MLGOLLRUSA-N
SMILES: O=C(O)C(N1[C@@]([H])([C@@H](C1=O)NC(CN(C=C(C2=O)Cl)C=C2Cl)=O)SC3)=C3CSC4=NN=C(S4)C
Biological Activity: Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cefazedone | 99.89% | Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria. | ||||||||||||||||||||
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Cefazedone (Standard) | ≥98% | Cefazedone (Standard) (Refosporen (Standard)) is the analytical standard of Cefazedone (HY-121144). This product is intended for research and analytical applications. Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria. | ||||||||||||||||||||
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References
- [1]. Gao L, et al. A Pharmacokinetic and Pharmacodynamic Study on Intravenous Cefazedone Sodium in Patients with Community-acquired Pneumonia. Chin Med J (Engl). 2015 May 5;128(9):1160-4. [Content Brief]
- [2]. Bloom JC, et al. Cephalosporin-induced immune cytopenia in the dog: demonstration of erythrocyte-, neutrophil-, and platelet-associated IgG following treatment with cefazedone. Am J Hematol. 1988 Jun;28(2):71-8. [Content Brief]
Keywords
