564483-18-7
564483-18-7
Chemical Structure
XPhos
Synonym(s): 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
- CAS No.: 564483-18-7
- Formula:C33H49P
- Molecular Weight:476.72
IUPAC Name: dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphane
InChIKey: UGOMMVLRQDMAQQ-UHFFFAOYSA-N
SMILES: CC(C)C1=CC(C(C)C)=CC(C(C)C)=C1C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4
Biological Activity: XPhos is a dual aryl monophosphine ligand. XPhos is an efficient and stable palladium catalytic ligand. XPhos can be used for amination of aryl sulfonate esters[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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XPhos | 99.20% | XPhos is a dual aryl monophosphine ligand. XPhos is an efficient and stable palladium catalytic ligand. XPhos can be used for amination of aryl sulfonate esters. | ||||||||||||||||||||
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BAY-27-9955 | 99.68% | BAY-27-9955 is an orally active non-peptide glucagon receptor antagonist. Bay 27-9955 competitively blocks the interaction of glucagon with the human glucagonreceptor at an IC50 value of 110 nM. BAY-27-9955 can be used for the study of type 2 diabetes. | ||||||||||||||||||||
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Tricyclohexylphosphine | 99.0% | Tricyclohexylphosphine (Tricyclohexylphosphane) is a chemical intermediate. The Tricyclohexylphosphine gold (I) n-mercaptobenzoate complex synthesized from Tricyclohexylphosphine induces ROS production and exhibits antiproliferative activity against breast cancer cells. | ||||||||||||||||||||
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Cyjohnphos | 98.0% | CyJohnPhos (2-(Dicyclohexylphosphino)biphenyl) is an organophosphine ligand. Gold (I) complexes derived from CyJohnPhos exhibit anti-colon cancer activity, inhibit the enzymatic activities of COX-1/COX-2 and TrxR, upregulate ROS levels, induce cell apoptosis, and some derivatives can induce cell cycle arrest. CyJohnPhos can serve as an intermediate for research related to organic synthesis. | ||||||||||||||||||||
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DavePhos | 98.0% | DavePhos is a phosphine ligand and electron donor. DavePhos can form cationic rhodium complexes to promote the selective hydrocarboxylation of styrene derivatives with CO2 and H2. As a sacrificial electron donor, DavePhos assists in generating active Rh-H species to initiate the catalytic cycle. DavePhos can be used in Buchwald−Hartwig cross-coupling reactions within palladium-based catalytic systems. DavePhos is applicable to platinum-catalyzed reductive amination of amine-acid. | ||||||||||||||||||||
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JohnPhos | 99.26% | JohnPhos is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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RuPhos | 99.65% | RuPhos is a Buchwald ligand. In aqueous Suzuki-Miyaura catalytic transfer polymerization, RuPhos forms inactive Pd (RuPhos)2 with palladium and inhibits diffusion to improve polymerization controllability. RuPhos additional addition in anhydrous Kumada polymerization exacerbates catalyst deactivation and chain transfer, significantly impairing polymerization control. | ||||||||||||||||||||
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MePhos | 98.0% | MePhos is an o-BPP ligand. The combination of MePhos and silver carbonate serves as a catalyst for H/D exchange reactions. | ||||||||||||||||||||
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Cyclohexyldiphenylphosphine | 99.99% | Cyclohexyldiphenylphosphine is a chemical compound commonly used as a ligand in coordination chemistry and organometallic synthesis. Cyclohexyldiphenylphosphine facilitates various catalytic reactions through acting as a stabilizing agent. Cyclohexyldiphenylphosphine is a ligand for some nickel(II) complexes. Cyclohexyldiphenylphosphine exhibits anti-cancer properties against SNO cancer cells when formed complex with silver. | ||||||||||||||||||||
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2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole | 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole (CM-Phos) is an organic compound with catalytic activity. 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole can be used as an efficient catalyst for cross-coupling reactions of various alcohols and olefins. 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole shows important application potential in pharmaceutical and material science. | |||||||||||||||||||||
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Dipropofol | 99.66% | Dipropofol is a dimeric derivative of Propofol (HY-B0649) with antioxidant and antibacterial activities. Dipropofol terminates free radical chain reactions, scavenges DPPH free radicals and inhibits lipid peroxidation. Dipropofol protects cells from death induced by glutamate, Aβ(25-35) and buthionine sulfoximine, and increases the survival rate of mice exposed to oxygen. Dipropofol selectively activates tonic GABAA currents, hyperpolarizes resting membrane potential, reduces action potential firing, and alleviates the severity of seizures induced by Kainic acid. Dipropofol can be used in the research of Gram-positive bacterial infections, Alzheimer's disease, cerebral ischemia-related neuronal injury, oxygen toxicity and temporal lobe epilepsy. | ||||||||||||||||||||
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References
- [1]. Huang X, et al. Expanding Pd-catalyzed C-N bond-forming processes: the first amidation of aryl sulfonates, aqueous amination, and complementarity with Cu-catalyzed reactions. J Am Chem Soc. 2003 Jun 4;125(22):6653-5. [Content Brief]
- [2]. Kinzel T, et al. A new palladium precatalyst allows for the fast Suzuki-Miyaura coupling reactions of unstable polyfluorophenyl and 2-heteroaryl boronic acids. J Am Chem Soc. 2010 Oct 13;132(40):14073-5. [Content Brief]
