571194-06-4
Chemical Structure
Remisporine B
- CAS 番号: 571194-06-4
- Formula:C30H24O12
- Molecular Weight:576.50
IUPAC Name: dimethyl (6aR,6a1R,7S,8aS,14bS)-1,7,10-trihydroxy-3,12-dimethyl-9,15-dioxo-6,6a,7,9,14b,15-hexahydrodichromeno[3',2':2,3;3'',2'':4,5]indeno[1,7-bc]furan-7,8a(6a1H)-dicarboxylate
InChIKey: RRGJMIUFDPLICY-JJEZGDBSSA-N
SMILES: COC([C@]12[C@]3([H])[C@](C4=C(OC5=CC(C)=CC(O)=C5C4=O)C[C@@]3([H])[C@](O)(O2)C(OC)=O)([H])C6=C1C(C7=C(O)C=C(C)C=C7O6)=O)=O
Biological Activity: Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A (HY-P2149)-induced T-cell proliferation and LPS (HY-D1056)- induced B-cell proliferations of mouse splenic lymphocytes with IC50 of 30.1 µg/mL and 32.4 µg/mL[1].
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Remisporine B | Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A (HY-P2149)-induced T-cell proliferation and LPS (HY-D1056)- induced B-cell proliferations of mouse splenic lymphocytes with IC50 of 30.1 µg/mL and 32.4 µg/mL. | |||||||||||||||||||||
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