577-11-7
Chemical Structure
Docusate Sodium
Synonym(s): Dioctyl sulfosuccinate sodium salt
- CAS No.: 577-11-7
- Formula:C20H37NaO7S
- Molecular Weight:444.56
IUPAC Name: sodium 1,4-bis((2-ethylhexyl)oxy)-1,4-dioxobutane-2-sulfonate
InChIKey: APSBXTVYXVQYAB-UHFFFAOYSA-M
SMILES: O=C(OCC(CC)CCCC)C(S(=O)(O[Na])=O)CC(OCC(CC)CCCC)=O
Biological Activity: Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice[1][2].
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Docusate Sodium | 98.0% | Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice. | ||||||||||||||||||||
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Docusate Sodium (Standard) | 99.69% | Docusate (Sodium) (Standard) is the analytical standard of Docusate (Sodium). This product is intended for research and analytical applications. Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice. | ||||||||||||||||||||
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- [1]. Y Gong, et al. Preclinical evaluation of docusate as protective agent from herpes simplex viruses. Antiviral Res. 2001 Oct;52(1):25-32. [Content Brief]
- [2]. Alexis M Temkin, et al. Increased adiposity, inflammation, metabolic disruption and dyslipidemia in adult male offspring of DOSS treated C57BL/6 dams. Sci Rep. 2019 Feb 6;9(1):1530. [Content Brief]
