58020-43-2
58020-43-2
Chemical Structure
HOKU-81
Synonym(s): 4-Hydroxytulobuterol
- CAS No.: 58020-43-2
- Formula:C12H18ClNO2
- Molecular Weight:243.73
IUPAC Name: 4-(2-(tert-butylamino)-1-hydroxyethyl)-3-chlorophenol
InChIKey: LIXBJWRFCNRAPA-UHFFFAOYSA-N
SMILES: ClC1=C(C(O)CNC(C)(C)C)C=CC(O)=C1
Biological Activity: HOKU-81 (4-Hydroxytulobuterol) is one of the metabolites of Tulobuterol (HY-B1810). HOKU-81 is a potent and selective β2-adrenoceptor stimulant. HOKU-81 has bronchodilating effect[1][2].
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HOKU-81 | 95.0% | HOKU-81 (4-Hydroxytulobuterol) is one of the metabolites of Tulobuterol (HY-B1810). HOKU-81 is a potent and selective β2-adrenoceptor stimulant. HOKU-81 has bronchodilating effect. | ||||||||||||||||||||
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HOKU-81 (Standard) | ≥98% | HOKU-81 (Standard) is the analytical standard of HOKU-81. This product is intended for research and analytical applications. HOKU-81 (4-Hydroxytulobuterol) is one of the metabolites of Tulobuterol (HY-B1810). HOKU-81 is a potent and selective β2-adrenoceptor stimulant. HOKU-81 has bronchodilating effect. | ||||||||||||||||||||
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References
- [1]. Kubo S, Matsubara I, Yamazaki M et al. Pharmacological studies of 1-(2-chloro-4-hydroxyphenyl)-2-t-butylaminoethanol (HOKU-81), a new bronchodilator. 1st Communication: Bronchodilator and cardiovascular actions. Arzneimittelforschung. 1980;30(8):1272-8. [Content Brief]
- [2]. Gomi Y, Shirahase H, Funato H. Effects of 1-(2-chloro-4-hydroxyphenyl)-t-butylaminoethanol (HOKU-81), a new bronchodilator, on isolated trachea and atria of guinea pig. Jpn J Pharmacol. 1979 Aug;29(4):515-24. [Content Brief]
Keywords
