597544-21-3
597544-21-3
Chemical Structure
Multi-kinase-IN-12
- CAS No.: 597544-21-3
- Formula:C23H23N5O2
- Molecular Weight:401.47
IUPAC Name: 4-(2-(4-(3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenoxy)ethyl)morpholine
InChIKey: OOQJIJYKWXLQNC-UHFFFAOYSA-N
SMILES: N=1C=CC(=CC1)C=2C=NN3C=C(C=NC23)C=4C=CC(OCCN5CCOCC5)=CC4
Biological Activity: Multi-kinase-IN-12 is a non-selective multi-target inhibitor, with IC50 values against human targets as follows: Flt3 < 0.001 μM, c-Src 0.002 μM, KDR 0.004 μM, Eph-A2, MNK-1 and Flt1 0.011 μM, Lck 0.016 μM, Rsk1 0.21 μM, and α2 subunit of AMPK 0.041 μM. Multi-kinase-IN-12 can be used in research related to solid tumors[1].
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Multi-kinase-IN-12 | Multi-kinase-IN-12 is a non-selective multi-target inhibitor, with IC50 values against human targets as follows: Flt3 < 0.001 μM, c-Src 0.002 μM, KDR 0.004 μM, Eph-A2, MNK-1 and Flt1 0.011 μM, Lck 0.016 μM, Rsk1 0.21 μM, and α2 subunit of AMPK 0.041 μM. Multi-kinase-IN-12 can be used in research related to solid tumors. | |||||||||||||||||||||
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