607363-34-8
Chemical Structure
(Rac)-Medicarpin
Synonym(s): 3-Hydroxy-9-methoxypterocarpan
- CAS No.: 607363-34-8
- Formula:C16H14O4
- Molecular Weight:270.28
IUPAC Name: 9-methoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3-ol
InChIKey: NSRJSISNDPOJOP-UHFFFAOYSA-N
SMILES: OC1=CC=C2C(OC3=CC(OC)=CC=C34)C4COC2=C1
Biological Activity: (Rac)-Medicarpin (3-Hydroxy-9-methoxypterocarpan) is a pterocarpan isoflavonoid phytoalexin with antimicrobial activity and anti-tumor promoting activity. (Rac)-Medicarpin induces apoptosis in human peripheral blood mononuclear cells. (Rac)-Medicarpin is also a defensive secondary metabolite produced in sword bean calli in response to exposure to spore suspensions of the non-pathogenic fungus Pithomyces chartarum or HgCl2[1][2].
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(Rac)-Medicarpin | (Rac)-Medicarpin (3-Hydroxy-9-methoxypterocarpan) is a pterocarpan isoflavonoid phytoalexin with antimicrobial activity and anti-tumor promoting activity. (Rac)-Medicarpin induces apoptosis in human peripheral blood mononuclear cells. (Rac)-Medicarpin is also a defensive secondary metabolite produced in sword bean calli in response to exposure to spore suspensions of the non-pathogenic fungus Pithomyces chartarum or HgCl2. | |||||||||||||||||||||
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References
- [1]. Ngamrojanavanich N, et al. Cytotoxic constituents from Butea superba Roxb. Journal of ethnopharmacology. 2007 Jan 19;109(2):354-8. [Content Brief]
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[2]. Gustine DL, Sherwood RT. Regulation of Phytoalexin Synthesis in Jackbean Callus Cultures: Stimulation of Phenylalanine Ammonia-Lyase and o-Methyltransferase. Plant Physiol. 1978 Feb;61(2):226-30.
[Content Brief]
