610318-54-2
610318-54-2
Chemical Structure
RGX-104
Synonym(s): Abequolixron
- CAS No.: 610318-54-2
- Formula:C34H33ClF3NO3
- Molecular Weight:596.08
IUPAC Name: (R)-2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)butoxy)phenyl)acetic acid
InChIKey: ZLJZDYOBXVOTSA-XMMPIXPASA-N
SMILES: O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4=CC=CC=C4)C)=C1
Biological Activity: RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene.
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RGX-104 | 99.76% | RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. | ||||||||||||||||||||
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RGX-104 (Standard) | ≥98% | RGX-104 (Standard) is the analytical standard of RGX-104 (HY-111498A). This product is intended for research and analytical applications. RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-111498RGX-104 hydrochloride -
Similarity Score 0.88
HY-10627RGW3965 (Standard) -
Similarity Score 0.87
HY-10627ARGW3965 hydrochloride (Standard) -
Similarity Score 0.83
HY-154928GW6340 -
Similarity Score 0.51
HY-134656BC1618 -
Similarity Score 0.51
HY-120846CHIR 4531 -
Similarity Score 0.50
HY-W708197Tolterodine dimer -
Similarity Score 0.50
HY-A0257APrenylamine lactate -
Similarity Score 0.50
HY-124168PF-244 -
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