613260-13-2
Chemical Structure
AVE5688
- CAS No.: 613260-13-2
- Formula:C16H8ClF5N2O5
- Molecular Weight:438.69
IUPAC Name: 4-(3-(2-chloro-4,5-difluorobenzoyl)ureido)-3-(trifluoromethoxy)benzoic acid
InChIKey: NWQGDIBCFLDHDO-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(NC(NC(C2=CC(F)=C(F)C=C2Cl)=O)=O)C(OC(F)(F)F)=C1
Biological Activity: AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes.
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AVE5688 | 98.79% | AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes. | ||||||||||||||||||||
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Keywords