622-78-6
622-78-6
Chemical Structure
Benzyl isothiocyanate
- CAS No.: 622-78-6
- Formula:C8H7NS
- Molecular Weight:149.21
IUPAC Name: (isothiocyanatomethyl)benzene
InChIKey: MDKCFLQDBWCQCV-UHFFFAOYSA-N
SMILES: S=C=NCC1=CC=CC=C1
Biological Activity: Benzyl isothiocyanate is an orally available isothiocyanate with bactericidal, anticancer, antiangiogenic and anthelmintic activities. Benzyl isothiocyanate exerts anticancer functions by regulating multiple signaling pathways, including apoptosis, cell proliferation, cell cycle arrest, metastasis, angiogenesis, and autophagy. In addition, Benzyl isothiocyanate can enhance muscle insulin sensitivity to improve obesity-induced hyperglycemia[1][2][3][4][5][6][7][8][9].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Benzyl isothiocyanate | 99.62% | Benzyl isothiocyanate is an orally available isothiocyanate with bactericidal, anticancer, antiangiogenic and anthelmintic activities. Benzyl isothiocyanate exerts anticancer functions by regulating multiple signaling pathways, including apoptosis, cell proliferation, cell cycle arrest, metastasis, angiogenesis, and autophagy. In addition, Benzyl isothiocyanate can enhance muscle insulin sensitivity to improve obesity-induced hyperglycemia. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Benzyl isothiocyanate (Standard) | ≥98% | Benzyl isothiocyanate (Standard) is the analytical standard of Benzyl isothiocyanate. This product is intended for research and analytical applications. Benzyl isothiocyanate is an orally available isothiocyanate with bactericidal, anticancer, antiangiogenic and anthelmintic activities. Benzyl isothiocyanate exerts anticancer functions by regulating multiple signaling pathways, including apoptosis, cell proliferation, cell cycle arrest, metastasis, angiogenesis, and autophagy. In addition, Benzyl isothiocyanate can enhance muscle insulin sensitivity to improve obesity-induced hyperglycemia. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Benzyl isothiocyanate-d7 | Benzyl isothiocyanate-d7 is the deuterium labeled Benzyl isothiocyanate. Benzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity. Benzyl isothiocyanate potent inhibits cell mobility, migration and invasion nature and matrix metalloproteinase-2 (MMP-2) activity of murine melanoma cells. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Abdel-Kader MS, et al. Quantitative Analysis of Benzyl Isothiocyanate in Salvadora persica Extract and Dental Care Herbal Formulations Using Reversed Phase C18 High-Performance Liquid Chromatography Method. Pharmacogn Mag. 2017 Oct;13(Suppl 3):S412-S416. [Content Brief]
- [2]. Lai KC, et al. Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro. Int J Oncol. 2017 Sep;51(3):832-840. [Content Brief]
- [3]. Dinh T N, et al. Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review[J]. Pharmacological Research, 2021, 169: 105666. [Content Brief]
- [4]. Kassie F, et al. Genotoxic effects of benzyl isothiocyanate, a natural chemopreventive agent[J]. Mutagenesis, 1999, 14(6): 595-604. [Content Brief]
- [5]. Kermanshai R, et al. Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts[J]. Phytochemistry, 2001, 57(3): 427-435. [Content Brief]
- [6]. Jensen J, et al. The toxic effects of benzyl glucosinolate and its hydrolysis product, the biofumigant benzyl isothiocyanate, to Folsomia fimetaria[J]. Environmental Toxicology and Chemistry, 2010, 29(2): 359-364. [Content Brief]
- [7]. Pintão A M, et al. In vitro and in vivo antitumor activity of benzyl isothiocyanate: a natural product from Tropaeolum majus[J]. Planta Medica, 1995, 61(03): 233-236. [Content Brief]
- [8]. Chuang W T, et al. Benzyl isothiocyanate ameliorates high-fat diet-induced hyperglycemia by enhancing Nrf2-dependent antioxidant defense-mediated IRS-1/AKT/TBC1D1 signaling and GLUT4 expression in skeletal muscle[J]. Journal of agricultural and food chemistry, 2020, 68(51): 15228-15238. [Content Brief]
- [9]. Dinh T N, et al. Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review[J]. Pharmacological Research, 2021, 169: 105666.
