625403-59-0
625403-59-0
Chemical Structure
SBI-183
- CAS No.: 625403-59-0
- Formula:C18H20N2O2
- Molecular Weight:296.36
InChIKey: ZZJGTLJERDOEQV-UHFFFAOYSA-N
SMILES: O=C(C1=CC(OC)=CC=C1)NC2=CC=C(N3CCCC3)C=C2
Biological Activity: SBI-183 is an orally active inhibitor of QSOX1 (Kd: 20 μM). SBI-183 suppresses the proliferative and invasive phenotype of renal cancer cell lines, including triple negative breast cancer cell line, lung adenocarcinoma cell line and pancreatic ductal adenocarcinoma. SBI-183 inhibits tumor growth in two human xenograft mouse models of renal cell carcinoma in vivo [1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SBI-183 | 99.8% | SBI-183 is an orally active inhibitor of QSOX1 (Kd: 20 μM). SBI-183 suppresses the proliferative and invasive phenotype of renal cancer cell lines, including triple negative breast cancer cell line, lung adenocarcinoma cell line and pancreatic ductal adenocarcinoma. SBI-183 inhibits tumor growth in two human xenograft mouse models of renal cell carcinoma in vivo . | ||||||||||||||||||||
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Structural Analogs
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Similarity Score 0.69
HY-W011774N-(p-Chlorobenzoyl)-p-anisidine -
Similarity Score 0.67
HY-W011532Itraconazole impurity 15 -
Similarity Score 0.66
HY-153017HIF-1 inhibitor-4 -
Similarity Score 0.65
HY-157563Dopamine D4 receptor ligand 2 -
Similarity Score 0.65
HY-W309310Etofesalamide -
Similarity Score 0.65
HY-144802DDO-02001 -
Similarity Score 0.64
HY-164764ADX61623 -
Similarity Score 0.64
HY-169708PRMT5-IN-49 -
Similarity Score 0.64
HY-179721CCKBR agonist-2 -
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