627908-92-3
627908-92-3
Chemical Structure
SU14813
- CAS No.: 627908-92-3
- Formula:C23H27FN4O4
- Molecular Weight:442.48
IUPAC Name: (S,E)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
InChIKey: CTNPALGJUAXMMC-HKJBKDEOSA-N
SMILES: O=C(/C(C1=C2)=C/C3=C(C(C(NC[C@H](O)CN4CCOCC4)=O)=C(N3)C)C)NC1=CC=C2F
Biological Activity: SU14813 is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT.
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SU14813 | 99.11% | SU14813 is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT. | ||||||||||||||||||||
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SU14813 (Standard) | ≥98% | SU14813 (Standard) is the analytical standard of SU14813 (HY-10501). This product is intended for research and analytical applications. SU14813 is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-10501B(Z)-SU14813 -
Similarity Score 0.88
HY-10501ASU14813 maleate -
Similarity Score 0.78
HY-10330RToceranib (Standard) -
Similarity Score 0.76
HY-10330ARToceranib phosphate (Standard) -
Similarity Score 0.75
HY-155943AMPK-IN-4 -
Similarity Score 0.74
HY-138032SU11657 -
Similarity Score 0.74
HY-138813A(E/Z)-N-Desethylsunitinib hydrochloride -
Similarity Score 0.74
HY-10873RN-Desethyl Sunitinib (Standard) -
Similarity Score 0.74
HY-13645Henatinib -
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