635-12-1
635-12-1
Chemical Structure
1,4-Anthraquinone
- CAS No.: 635-12-1
- Formula:C14H8O2
- Molecular Weight:208.21
IUPAC Name: anthracene-1,4-dione
InChIKey: LSOTZYUVGZKSHR-UHFFFAOYSA-N
SMILES: O=C1C=CC(C2=C1C=C3C=CC=CC3=C2)=O
Biological Activity: 1,4-Anthraquinone is a potent anticancer agent. 1,4-Anthraquinone blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of cancer cells. 1,4-Anthraquinone can be used to research anti-leukemia[1].
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1,4-Anthraquinone | 96.22% | 1,4-Anthraquinone is a potent anticancer agent. 1,4-Anthraquinone blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of cancer cells. 1,4-Anthraquinone can be used to research anti-leukemia. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.66
HY-1114411,4-Chrysenequinone -
Similarity Score 0.66
HY-N0354Anthraquinone -
Similarity Score 0.64
HY-N1739RTectoquinone (Standard) -
Similarity Score 0.64
HY-W014139Naphthalene-2,3-dicarboxylic acid -
Similarity Score 0.64
HY-177910Anticoronavirus agent-1 -
Similarity Score 0.64
HY-W456500Anthracene-2,3-dicarboxylic acid -
Similarity Score 0.64
HY-146487Anti-infective agent 1 -
Similarity Score 0.62
HY-W456516Anthracene-1,4-dicarboxylic acid -
Similarity Score 0.62
HY-101329Anthracene-9-carboxylic acid -
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References
- [1]. Perchellet EM, et al. 1,4-Anthraquinone: an anticancer drug that blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of L1210 leukemic cells in the same nanomolar range as daunorubicin in vitro. Anticancer Drugs. 2000 Jun;11(5):339-52. [Content Brief]
