64567-60-8
64567-60-8
Chemical Structure
Thalidomide-5-OH
- CAS No.: 64567-60-8
- Formula:C13H10N2O5
- Molecular Weight:274.23
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione
InChIKey: LJBQRRQTZUJWRC-UHFFFAOYSA-N
SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(O)=C3)=O
Biological Activity: Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs[1].
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Thalidomide-5-OH | 98.23% | Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs. | ||||||||||||||||||||
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Thalidomide-5-OH (Standard) | 99.43% | Thalidomide-5-OH (Standard) is the analytical standard of Thalidomide-5-OH. This product is intended for research and analytical applications. Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-W457158(S)-Thalidomide-5-OH -
Similarity Score 0.87
HY-W586331Thalidomide-iodo -
Similarity Score 0.87
HY-W454632Thalidomide-5-Cl -
Similarity Score 0.87
HY-139548Thalidomide-5-methyl -
Similarity Score 0.86
HY-W087383Thalidomide 5-fluoride -
Similarity Score 0.86
HY-W0235735-Aminothalidomide -
Similarity Score 0.86
HY-W069604Thalidomide-5-Br -
Similarity Score 0.86
HY-W6744355-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione -
Similarity Score 0.85
HY-W586327Thalidomide-5-methanol -
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