Thalidomide-iodo

Cat. No.: HY-W586331 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
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Thalidomide-iodo is an iodinated E3 ligase activator. Thalidomide-iodo can be used for further derivitization by substitution of iodine.

For research use only. We do not sell to patients.

Thalidomide-iodo Chemical Structure

CAS No. : 2509137-01-1

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	Get quote
10 g	Get quote

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•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Ligands for E3 Ligase Isoform Specific Products:

View All Isoforms

von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B

Biological Activity
Purity & Documentation
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Description

Thalidomide-iodo is an iodinated E3 ligase activator. Thalidomide-iodo can be used for further derivitization by substitution of iodine.

Molecular Weight

384.13

Formula

C₁₃H₉IN₂O₄

CAS No.

2509137-01-1

Appearance

Solid

Color

Gray to dark gray

SMILES

O=C1C2=CC=C(C=C2C(N1C3C(NC(CC3)=O)=O)=O)I

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (260.33 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6033 mL	13.0164 mL	26.0329 mL
5 mM	0.5207 mL	2.6033 mL	5.2066 mL
10 mM	0.2603 mL	1.3016 mL	2.6033 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.0%

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Data Sheet (244 KB) SDS (393 KB)

COA (250 KB) HNMR (133 KB) MS (190 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6033 mL	13.0164 mL	26.0329 mL	65.0821 mL
	5 mM	0.5207 mL	2.6033 mL	5.2066 mL	13.0164 mL
	10 mM	0.2603 mL	1.3016 mL	2.6033 mL	6.5082 mL
	15 mM	0.1736 mL	0.8678 mL	1.7355 mL	4.3388 mL
	20 mM	0.1302 mL	0.6508 mL	1.3016 mL	3.2541 mL
	25 mM	0.1041 mL	0.5207 mL	1.0413 mL	2.6033 mL
	30 mM	0.0868 mL	0.4339 mL	0.8678 mL	2.1694 mL
	40 mM	0.0651 mL	0.3254 mL	0.6508 mL	1.6271 mL
	50 mM	0.0521 mL	0.2603 mL	0.5207 mL	1.3016 mL
	60 mM	0.0434 mL	0.2169 mL	0.4339 mL	1.0847 mL
	80 mM	0.0325 mL	0.1627 mL	0.3254 mL	0.8135 mL
	100 mM	0.0260 mL	0.1302 mL	0.2603 mL	0.6508 mL