65-49-6
65-49-6
Chemical Structure
4-Aminosalicylic acid
- CAS. Nr.: 65-49-6
- Formula:C7H7NO3
- Molecular Weight:153.14
IUPAC Name: 4-amino-2-hydroxybenzoic acid
InChIKey: WUBBRNOQWQTFEX-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(N)C=C1O
Biological Activity: 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active[1][1][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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4-Aminosalicylic acid | 99.82% | 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active. | ||||||||||||||||||||
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4-Aminosalicylic acid (Standard) | ≥98% | 4-Aminosalicylic acid (Standard) is the analytical standard of 4-Aminosalicylic acid. This product is intended for research and analytical applications. 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active. | ||||||||||||||||||||
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4-Aminosalicylic acid-d6 | 4-Aminosalicylic acid-d6 is the deuterium labeled 4-Aminosalicylic acid (HY-I0447). 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active. | |||||||||||||||||||||
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References
- [1]. Zheng J, et al. para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. J Biol Chem. 2013 Aug 9;288(32):23447-56. [Content Brief]
- [3]. Dhaneshwar SS. Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease. World J Gastroenterol. 2014 Apr 7;20(13):3564-71. [Content Brief]
