66051-76-1
Chemical Structure
(-)-Halofantrine
Synonym(s): (-)-SKF-102886 free base; (-)-WR-171669
- CAS No.: 66051-76-1
- Formula:C26H30Cl2F3NO
- Molecular Weight:500.42
SMILES: OC(CCN(CCCC)CCCC)C1=CC2=C(Cl)C=C(Cl)C=C2C3=CC(C(F)(F)F)=CC=C31.[Rotation (-)]
Biological Activity: (-)-Halofantrine ((-)-SKF-102886 free base; (-)-WR-171669) is an inhibitor of the malignant malaria parasite (P. falciparum) and targets multidrug-resistant P. falciparum. The pharmacokinetic parameters of (-)-Halofantrine in rats vary depending on the route of administration, distinguishing it from other isomers[1].
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(-)-Halofantrine | (-)-Halofantrine ((-)-SKF-102886 free base; (-)-WR-171669) is an inhibitor of the malignant malaria parasite (P. falciparum) and targets multidrug-resistant P. falciparum. The pharmacokinetic parameters of (-)-Halofantrine in rats vary depending on the route of administration, distinguishing it from other isomers. | |||||||||||||||||||||
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Keywords