668980-17-4
668980-17-4
Chemical Structure
CCR4 antagonist 4
- CAS No.: 668980-17-4
- Formula:C24H27Cl2N7O
- Molecular Weight:500.42
InChIKey: GDQQUDANFRCFMF-HXUWFJFHSA-N
SMILES: ClC(C=C(C=C1)Cl)=C1CNC2=NC(N3CCN(CC3)C([C@H]4CCCCN4)=O)=NC5=C2C=CC=N5
Biological Activity: CCR4 antagonist 4 (compound 22) is a selective and potent antagonist of the CC chemokine receptor-4 (CCR4), with an IC50 of 0.02 μM. CCR4 antagonist 4 also blocks MDC-mediated chemotaxis (IC50: 0.007 μM) and Ca2+ mobilization (IC50: 0.003 μM). CCR4 antagonist 4 can be used for allergic inflammation research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CCR4 antagonist 4 | 98.92% | CCR4 antagonist 4 (compound 22) is a selective and potent antagonist of the CC chemokine receptor-4 (CCR4), with an IC50 of 0.02 μM. CCR4 antagonist 4 also blocks MDC-mediated chemotaxis (IC50: 0.007 μM) and Ca2+ mobilization (IC50: 0.003 μM). CCR4 antagonist 4 can be used for allergic inflammation research. | ||||||||||||||||||||
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References
Keywords
