668980-17-4

CCR4 antagonist 4 Chemical Structure
668980-17-4

Chemical Structure

CCR4 antagonist 4

  • CAS No.: 668980-17-4
  • Formula:C24H27Cl2N7O
  • Molecular Weight:500.42

InChIKey: GDQQUDANFRCFMF-HXUWFJFHSA-N

SMILES: ClC(C=C(C=C1)Cl)=C1CNC2=NC(N3CCN(CC3)C([C@H]4CCCCN4)=O)=NC5=C2C=CC=N5

Biological Activity: CCR4 antagonist 4 is a selective CCR4 antagonist with an IC50 of 0.02 μM that blocks MDC/CCL22-mediated signaling. CCR4 antagonist 4 blocks MDC-mediated chemotaxis and calcium mobilization and reduces eosinophil infiltration into the allergic pulmonary airway in mouse models. CCR4 antagonist 4 can be used for research on allergic pulmonary inflammation[1].

Cat. No. Product Name Purity Description Pricing
HY-157453 		CCR4 antagonist 4 98.92% CCR4 antagonist 4 is a selective CCR4 antagonist with an IC50 of 0.02 μM that blocks MDC/CCL22-mediated signaling. CCR4 antagonist 4 blocks MDC-mediated chemotaxis and calcium mobilization and reduces eosinophil infiltration into the allergic pulmonary airway in mouse models. CCR4 antagonist 4 can be used for research on allergic pulmonary inflammation.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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