68220-27-9
68220-27-9
Chemical Structure
SBI-0802767
- CAS 番号: 68220-27-9
- Formula:C12H9Cl2N5
- Molecular Weight:294.14
InChIKey: OQNSRMIDLWWUGD-UHFFFAOYSA-N
SMILES: ClC1=CC=CC(Cl)=C1CN2C=NC(N)=C3N=CN=C32
Biological Activity: SBI-0802767 is an orally active, uncompetitive and highly selective inhibitor of protein tyrosine phosphatase (LMPTP) with an IC50 of 0.239 μM. SBI-0802767 exhibits >1000-fold selectivity over other protein tyrosine phosphatases and enhances insulin signaling in hepatocytes. SBI-0802767 is used in studies of obesity-related type 2 diabetes and insulin resistance[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SBI-0802767 | SBI-0802767 is an orally active, uncompetitive and highly selective inhibitor of protein tyrosine phosphatase (LMPTP) with an IC50 of 0.239 μM. SBI-0802767 exhibits >1000-fold selectivity over other protein tyrosine phosphatases and enhances insulin signaling in hepatocytes. SBI-0802767 is used in studies of obesity-related type 2 diabetes and insulin resistance. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
