68341-14-0
68341-14-0
Chemical Structure
Cu(II)GTSM
- CAS No.: 68341-14-0
- Formula:C6H10CuN6S2
- Molecular Weight:293.86
InChIKey: ILQDIMXONQDSFP-RUACYTINSA-L
SMILES: CNC1=N[N]2=CC=[N]3N=C(NC)[S-][Cu+2]23[S-]1
Biological Activity: Cu(II)GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3β. Cu(II)GTSM inhibits Amyloid-β oligomers (AβOs) and decreases tau phosphorylation. Cu(II)GTSM also decreases the abundance of Amyloid-β trimers. Cu(II)GTSM is a potential anticancer and antimicrobial agent[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cu(II)GTSM | 95% | Cu(II)GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3β. Cu(II)GTSM inhibits Amyloid-β oligomers (AβOs) and decreases tau phosphorylation. Cu(II)GTSM also decreases the abundance of Amyloid-β trimers. Cu(II)GTSM is a potential anticancer and antimicrobial agent. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.54
HY-W460407N,N'-Dimethylhydrazine dihydrochloride -
Similarity Score 0.54
HY-Y1684N,N'-Dimethyl-1,3-propylenediamine -
Similarity Score 0.53
HY-W088621N1,N4-Dimethylbutane-1,4-diamine -
Similarity Score 0.53
HY-W098350N1,N6-Dimethylhexane-1,6-diamine -
Similarity Score 0.53
HY-106634Mitoguazone -
Similarity Score 0.53
HY-W1512802-Cyano-1,3-dimethylguanidine -
Similarity Score 0.53
HY-W027951RN,N'-Dimethylthiourea (Standard) -
Similarity Score 0.52
HY-130212Amobam -
Similarity Score 0.52
HY-W127636Tetraethylammonium fluoride tetrahydrofluoride -
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References
- [1]. Andres SA, et al. Synthesis, Characterization, and Biological Activity of Hybrid Thiosemicarbazone-Alkylthiocarbamate Metal Complexes. Inorg Chem. 2020;59(7):4924-4935. [Content Brief]
- [2]. Crouch PJ, et al. Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation. Proc Natl Acad Sci U S A. 2009;106(2):381-386. [Content Brief]
