690216-38-7
690216-38-7
Chemical Structure
Inh2-B1
- CAS No.: 690216-38-7
- Formula:C19H13N3O4S2
- Molecular Weight:411.45
IUPAC Name: methyl 5-oxo-3-(phenylcarbamoyl)-1-thioxo-4,5-dihydro-1H-thiazolo[3,4-a]quinazoline-8-carboxylate
InChIKey: WKFXKJMYGNYRPR-UHFFFAOYSA-N
SMILES: O=C(C1=CC(N2C(N3)=C(C(NC4=CC=CC=C4)=O)SC2=S)=C(C=C1)C3=O)OC
Biological Activity: Inh2-B1 is a Ser/Thr protein kinase (STK1) inhibitor. Inh2-B1 specifically inhibits STK1 activity by directly binding to its ATP-binding catalytic domain. Inh2-B1 down-regulates cell wall hydrolase genes and disrupts the biofilm formation of Methicillin-resistant Staphylococcus aureus (MRSA) clearly[1].
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Inh2-B1 | Inh2-B1 is a Ser/Thr protein kinase (STK1) inhibitor. Inh2-B1 specifically inhibits STK1 activity by directly binding to its ATP-binding catalytic domain. Inh2-B1 down-regulates cell wall hydrolase genes and disrupts the biofilm formation of Methicillin-resistant Staphylococcus aureus (MRSA) clearly. | |||||||||||||||||||||
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