69280-94-0
Chemical Structure
Deoxypheganomycin D
- CAS No.: 69280-94-0
- Formula:C30H47N9O11
- Molecular Weight:709.75
IUPAC Name: ((S)-2-((S)-4-amino-2-((S)-2-(3,5-dihydroxy-4-methylphenyl)-2-guanidinoacetamido)-4-oxobutanamido)-3,3-dimethylbutanoyl)-L-lysyl-L-aspartic acid
InChIKey: VQHYEARHJYNYPS-OLZZFSTQSA-N
SMILES: OC(C[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](C(C)(C)C)NC([C@H](CC(N)=O)NC([C@H](C1=CC(O)=C(C(O)=C1)C)NC(N)=N)=O)=O)=O)=O)=O
Biological Activity: Deoxypheganomycin D is a specific antimycobacterial inhibitor with no cross-resistance to other antibiotics such as Paromomycin (HY-B0956), Capreomycin (HY-P3270), Viomycin (HY-A0155), Streptothricin (HY-129065), Kanamycin (HY-16566), and Streptomycin (HY-B1906). Deoxypheganomycin D (28 μM) partially inhibits the growth of Mycobacterium 607, with no significant inhibitory effects on DNA, RNA, or protein synthesis. Deoxypheganomycin D (7 μM) affects leucine influx, not thymidine, and has the opposite effect on efflux. The effects of Deoxypheganomycin D may be related to cell membrane and specific mycobacterial lipid components.
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Deoxypheganomycin D | Deoxypheganomycin D is a specific antimycobacterial inhibitor with no cross-resistance to other antibiotics such as Paromomycin (HY-B0956), Capreomycin (HY-P3270), Viomycin (HY-A0155), Streptothricin (HY-129065), Kanamycin (HY-16566), and Streptomycin (HY-B1906). Deoxypheganomycin D (28 μM) partially inhibits the growth of Mycobacterium 607, with no significant inhibitory effects on DNA, RNA, or protein synthesis. Deoxypheganomycin D (7 μM) affects leucine influx, not thymidine, and has the opposite effect on efflux. The effects of Deoxypheganomycin D may be related to cell membrane and specific mycobacterial lipid components. | |||||||||||||||||||||
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Keywords
