708258-16-6
708258-16-6
Chemical Structure
BMS-354326
- CAS No.: 708258-16-6
- Formula:C28H40N4O5
- Molecular Weight:512.64
IUPAC Name: (2S,3R)-4-oxo-1-(4-(6-phenylhexanoyl)piperazine-1-carbonyl)-3-(2-(piperidin-3-yl)ethyl)azetidine-2-carboxylic acid
InChIKey: XVYFBYVSZOCXRJ-OMQKAAQBSA-N
SMILES: O=C([C@H]([C@H]1CCC2CNCCC2)N(C(N3CCN(C(CCCCCC4=CC=CC=C4)=O)CC3)=O)C1=O)O
Biological Activity: BMS-354326 is a tryptase inhibitor with an IC50 of 1.8 nM. BMS-354326 exhibits excellent selectivity against trypsin and most other related serine proteases. BMS-354326 can be used in the research of asthma and inflammatory diseases[1].
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BMS-354326 | BMS-354326 is a tryptase inhibitor with an IC50 of 1.8 nM. BMS-354326 exhibits excellent selectivity against trypsin and most other related serine proteases. BMS-354326 can be used in the research of asthma and inflammatory diseases. | |||||||||||||||||||||
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