71018-03-6
71018-03-6
Chemical Structure
Cyclo(L-Ser-L-Val)
- CAS No.: 71018-03-6
- Formula:C8H14N2O3
- Molecular Weight:186.21
IUPAC Name: (3S,6S)-3-(hydroxymethyl)-6-isopropylpiperazine-2,5-dione
InChIKey: NJFKZURMUGDZGV-WDSKDSINSA-N
SMILES: C(C)(C)[C@H]1C(=O)N[C@@H](CO)C(=O)N1
Biological Activity: Cyclo(L-Ser-L-Val) is a cyclic dipeptide (diketopiperazine) that lacks growth-promoting activity for E. coli in SAPI-serum medium[1].Cyclo(L-Ser-L-Val) can be chemically synthesized as a precursor to cyclo(ΔAla-L-Val)[2].
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Cyclo(L-Ser-L-Val) | Cyclo(L-Ser-L-Val) is a cyclic dipeptide (diketopiperazine) that lacks growth-promoting activity for E. coli in SAPI-serum medium.Cyclo(L-Ser-L-Val) can be chemically synthesized as a precursor to cyclo(ΔAla-L-Val). | |||||||||||||||||||||
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References
- [1]. Burton CL, et al. The growth response of Escherichia coli to neurotransmitters and related catecholamine drugs requires a functional enterobactin biosynthesis and uptake system. Infect Immun. 2002;70(11):5913-5923. [Content Brief]
- [2]. Holden MT, et al. Quorum-sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other gram-negative bacteria. Mol Microbiol. 1999;33(6):1254-1266. [Content Brief]
