730960-98-2
Chemical Structure
NSC15520
- CAS No.: 730960-98-2
- Formula:C24H34O6
- Molecular Weight:418.52
IUPAC Name: (3R,4aR,4bR,8R,8aR,10aS,12S)-2-isopropyl-4b,8-dimethyl-4,4a,4b,5,6,7,8,8a,9,10-decahydro-3H-3,10a-ethanophenanthrene-8,11,12-tricarboxylic acid
InChIKey: PXYRCOIAFZBLBN-JYEBMZEQSA-N
SMILES: C[C@@]1(C(O)=O)CCC[C@]2(C)[C@]3([H])[C@]4(C(C(O)=O)[C@H]([C@@H](C3)C(C(C)C)=C4)C(O)=O)CC[C@@]12[H]
Biological Activity: NSC15520 is a small molecular inhibitor of Replication Protein A (RPA). NSC15520 specifically recognizes the RPA N-terminal DNA binding domain (DBD), and blocks the interaction of RPA with p53 or RAD9. NSC15520 also inhibtis helix destabilization of a duplex DNA (dsDNA) oligonucleotide, involves in DNA replication, DNA repair, DNA recombination, and DNA damage response signaling[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NSC15520 | 99.90% | NSC15520 is a small molecular inhibitor of Replication Protein A (RPA). NSC15520 specifically recognizes the RPA N-terminal DNA binding domain (DBD), and blocks the interaction of RPA with p53 or RAD9. NSC15520 also inhibtis helix destabilization of a duplex DNA (dsDNA) oligonucleotide, involves in DNA replication, DNA repair, DNA recombination, and DNA damage response signaling. | ||||||||||||||||||||
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