73681-12-6
73681-12-6
Chemical Structure
Indecainide hydrochloride
Synonym(s): Ricainide hydrochloride; LY 135837
- CAS No.: 73681-12-6
- Formula:C20H25ClN2O
- Molecular Weight:344.88
IUPAC Name: 9-(3-(isopropylamino)propyl)-9H-fluorene-9-carboxamide hydrochloride
InChIKey: NXNSCUZKMVYAJQ-UHFFFAOYSA-N
SMILES: O=C(C1(CCCNC(C)C)C2=C(C3=C1C=CC=C3)C=CC=C2)N.Cl
Biological Activity: Indecainide hydrochloride is a potent and orally active class I local anesthetic antiarrhythmic agent. Indecainide hydrochloride has Na+-channel-blocking activity[1][2][3].
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Indecainide hydrochloride | Indecainide hydrochloride is a potent and orally active class I local anesthetic antiarrhythmic agent. Indecainide hydrochloride has Na+-channel-blocking activity. | |||||||||||||||||||||
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References
- [1]. Steinberg MI, et al. Electrophysiological studies of indecainide hydrochloride, a new antiarrhythmic agent, in canine cardiac tissues. J Cardiovasc Pharmacol. 1984 Jul-Aug;6(4):614-21. [Content Brief]
- [2]. Sandusky GE Jr, et al. Toxicology of indecainide hydrochloride after intravenous administration to rats and dogs. Toxicol Lett. 1985 Aug;26(2-3):107-10. [Content Brief]
- [3]. D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14(3):454-61. [Content Brief]
Keywords
