74061-79-3
74061-79-3
Chemical Structure
Sesaminol
- CAS No.: 74061-79-3
- Formula:C20H18O7
- Molecular Weight:370.35
InChIKey: KQRXQIPRDKVZPW-ISZNXKAUSA-N
SMILES: OC1=C(C=C2C(OCO2)=C1)[C@@H]3[C@]4([H])[C@@](CO3)([H])[C@@H](C5=CC=C(OCO6)C6=C5)OC4
Biological Activity: Sesaminol is an orally active activator for Nrf2-ARE pathway, that promotes the the nuclear translocation of Nrf2 and enhances the NQO1 expression, thereby enhances the cell's defense against oxidative stress. Sesaminol inhibits 6-OHDA (HY-B1081)-induced ROS production and apoptosis in cell SH-SY5Y. Sesaminol exhibits neuroprotective efficacy against Rotenone (HY-B1756)-induced Parkinson's disease[1].
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Sesaminol | Sesaminol is an orally active activator for Nrf2-ARE pathway, that promotes the the nuclear translocation of Nrf2 and enhances the NQO1 expression, thereby enhances the cell's defense against oxidative stress. Sesaminol inhibits 6-OHDA (HY-B1081)-induced ROS production and apoptosis in cell SH-SY5Y. Sesaminol exhibits neuroprotective efficacy against Rotenone (HY-B1756)-induced Parkinson's disease. | |||||||||||||||||||||
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