752187-80-7
Chemical Structure
Taprenepag
Synonym(s): CP-544326
- CAS No.: 752187-80-7
- Formula:C24H22N4O5S
- Molecular Weight:478.52
IUPAC Name: 2-(3-((N-(4-(1H-pyrazol-1-yl)benzyl)pyridine-3-sulfonamido)methyl)phenoxy)acetic acid
InChIKey: MFFBXYNKZHTCEY-UHFFFAOYSA-N
SMILES: O=S(C1=CN=CC=C1)(N(CC2=CC(OCC(O)=O)=CC=C2)CC3=CC=C(N4C=CC=N4)C=C3)=O
Biological Activity: Taprenepag (CP-544326) is a potent and selective prostaglandin EP(2) agonist with IC50s of 10 and 15 nM for human and rat EP2, respectively. Taprenepag shows selectivity for EP2 over other EP receptors (IC50s>3200 nM for EP1, EP3, and EP4) and a panel of 37 G protein-coupled receptors[1].
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Taprenepag | 98.79% | Taprenepag (CP-544326) is a potent and selective prostaglandin EP(2) agonist with IC50s of 10 and 15 nM for human and rat EP2, respectively. Taprenepag shows selectivity for EP2 over other EP receptors (IC50s>3200 nM for EP1, EP3, and EP4) and a panel of 37 G protein-coupled receptors. | ||||||||||||||||||||
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Keywords
