775294-82-1
775294-82-1
Chemical Structure
SBE13
- CAS No.: 775294-82-1
- Formula:C24H27ClN2O4
- Molecular Weight:442.94
IUPAC Name: N-(4-((6-chloropyridin-3-yl)methoxy)-3-methoxybenzyl)-2-(3,4-dimethoxyphenyl)ethan-1-amine
InChIKey: XNPRQBVQOJZMMA-UHFFFAOYSA-N
SMILES: COC1=CC=C(CCNCC2=CC=C(OCC3=CC=C(Cl)N=C3)C(OC)=C2)C=C1OC
Biological Activity: SBE13 is a potent and selective Plk1 inhibitor, with an IC50 of 200 pM; SBE13 poorly inhibits Plk2 (IC50>66 μM) or Plk3 (IC50=875 nM).
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SBE13 | SBE13 is a potent and selective Plk1 inhibitor, with an IC50 of 200 pM; SBE13 poorly inhibits Plk2 (IC50>66 μM) or Plk3 (IC50=875 nM). | |||||||||||||||||||||
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