819827-50-4
819827-50-4
Chemical Structure
CB7993113
- CAS No.: 819827-50-4
- Formula:C15H10BrNO5
- Molecular Weight:364.15
IUPAC Name: 2-((2-(5-bromofuran-2-yl)-4-oxo-4H-chromen-3-yl)oxy)acetamide
InChIKey: KGIGMCONNWRUGX-UHFFFAOYSA-N
SMILES: O=C(N)COC1=C(C2=CC=C(Br)O2)OC3=CC=CC=C3C1=O
Biological Activity: CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CB7993113 | 98.0% | CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively. | ||||||||||||||||||||
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CB7993113 (Standard) | ≥98% | CB7993113 (Standard) is the analytical standard of CB7993113 (HY-111450). This product is intended for research and analytical applications. CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.66
HY-N131923-Acetoxyflavone -
Similarity Score 0.65
HY-N9499R3-Methoxyflavone (Standard) -
Similarity Score 0.63
HY-1557863,7-DMF -
Similarity Score 0.62
HY-1118034'-Methoxyflavonol -
Similarity Score 0.62
HY-N6629R3'-Methoxyflavonol (Standard) -
Similarity Score 0.62
HY-222043,2'-Dihydroxyflavone -
Similarity Score 0.61
HY-1118023,4'-Dihydroxyflavone -
Similarity Score 0.61
HY-143451Tyrosinase-IN-4 -
Similarity Score 0.61
HY-1118043',4'-Dihydroxyflavonol -
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