82147-31-7
82147-31-7
Chemical Structure
WR 151327
- CAS No.: 82147-31-7
- Formula:C7H19N2O3PS
- Molecular Weight:242.28
IUPAC Name: S-(3-((3-(methylamino)propyl)amino)propyl) O,O-dihydrogen phosphorothioate
InChIKey: RJCFTKZFLQWQQX-UHFFFAOYSA-N
SMILES: CNCCCNCCCSP(O)(O)=O
Biological Activity: WR 151327 is an orally active radiation and chemoprotection protector. WR 151327 can suppress expression of HIV. WR 151327 can be used for the researches of infection and cancer[1][2][3].
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WR 151327 | WR 151327 is an orally active radiation and chemoprotection protector. WR 151327 can suppress expression of HIV. WR 151327 can be used for the researches of infection and cancer. | |||||||||||||||||||||
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References
- [1]. Ledney GD, et al. WR-151327 increases resistance to Klebsiella pneumoniae infection in mixed-field- and gamma-photon-irradiated mice. Int J Radiat Biol. 2000 Feb;76(2):261-71. [Content Brief]
- [2]. Kalebic T, et al. Organic thiophosphate WR-151327 suppresses expression of HIV in chronically infected cells. AIDS Res Hum Retroviruses. 1994 Jun;10(6):727-33. [Content Brief]
- [3]. Green D, et al. Preclinical evaluation of WR-151327: an orally active chemotherapy protector. Cancer Res. 1994 Feb 1;54(3):738-41. [Content Brief]
