83364-03-8
83364-03-8
Chemical Structure
D 15413
- CAS No.: 83364-03-8
- Formula:C16H12Cl3NO2
- Molecular Weight:356.63
IUPAC Name: 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-1H-indol-6-ol
InChIKey: ZATDYQOGSPTLBG-UHFFFAOYSA-N
SMILES: ClC1=C(C=C(N2CC)C3=C(C=C(C=C3Cl)O)Cl)C2=CC(O)=C1
Biological Activity: D 15413 is an orally active antagonist for nonsteroidal estrogen. D 15413 inhibits growth of estrogen receptor positive MCF-7 cell with an inhibition rate of 70% at 10-7 M. D 15413 exhibits antitumor efficacy against DMBA (HY-W011845) or MNU (HY-34758)-induced breast cancer[1].
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D 15413 | D 15413 is an orally active antagonist for nonsteroidal estrogen. D 15413 inhibits growth of estrogen receptor positive MCF-7 cell with an inhibition rate of 70% at 10-7 M. D 15413 exhibits antitumor efficacy against DMBA (HY-W011845) or MNU (HY-34758)-induced breast cancer. | |||||||||||||||||||||
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References
Keywords
