836640-15-4
836640-15-4
Chemical Structure
PARP1-IN-8
- CAS No.: 836640-15-4
- Formula:C23H18ClN3O2
- Molecular Weight:403.86
IUPAC Name: N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide
InChIKey: BOYHFRMRSLOWLL-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(Cl)=C1)CCN(N=C(C2=CC=CC=C2)C3=C4C=CC=C3)C4=O
Biological Activity: PARP1-IN-8 (compound 11c) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 97 nM. PARP1-IN-8 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PARP1-IN-8 | 99.29% | PARP1-IN-8 (compound 11c) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 97 nM. PARP1-IN-8 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. | ||||||||||||||||||||
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References
Keywords
