844903-58-8
Chemical Structure
GSK163090
- CAS No.: 844903-58-8
- Formula:C25H29N5O
- Molecular Weight:415.53
IUPAC Name: 1-(3-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)phenyl)imidazolidin-2-one
InChIKey: ANGUXJDGJCHGOG-UHFFFAOYSA-N
SMILES: O=C1NCCN1C2=CC=CC(CCN3CCN(C4=C5C=CC(C)=NC5=CC=C4)CC3)=C2
Biological Activity: GSK163090 is a potent, selective and orally active 5-HT1A/1B/1D receptor antagonist with pKi values of 9.4, 8.5 and 9.7, respectively. GSK163090 inhibits the functional activity of serotonin reuptake transporter (SerT) with a pKi value of 6.1. GSK163090 has antidepressant and anxiolytic activities[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK163090 | 99.57% | GSK163090 is a potent, selective and orally active 5-HT1A/1B/1D receptor antagonist with pKi values of 9.4, 8.5 and 9.7, respectively. GSK163090 inhibits the functional activity of serotonin reuptake transporter (SerT) with a pKi value of 6.1. GSK163090 has antidepressant and anxiolytic activities. | ||||||||||||||||||||
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Keywords
