84731-70-4
84731-70-4
Chemical Structure
Eco-DEHCH
- CAS No.: 84731-70-4
- Formula:C24H44O4
- Molecular Weight:396.60
InChIKey: HOQGHOMLEVKTBY-UHFFFAOYSA-N
SMILES: O=C(C1CCC(CC1)C(OCC(CCCC)CC)=O)OCC(CCCC)CC
Biological Activity: Eco-DEHCH is a phthalate-free alternative plasticizer that safely and effectively softens plastics such as flexible PVC. Eco-DEHCH shows low binding affinity for various endocrine receptors, including estrogen, androgen, glucocorticoid, thyroid receptor α and thyroid receptor β. Eco-DEHCH causes dose-dependent accumulation of α2u-globulin in the kidneys of male Han Wistar rats, but has overall general safety[1][2].
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Eco-DEHCH | Eco-DEHCH is a phthalate-free alternative plasticizer that safely and effectively softens plastics such as flexible PVC. Eco-DEHCH shows low binding affinity for various endocrine receptors, including estrogen, androgen, glucocorticoid, thyroid receptor α and thyroid receptor β. Eco-DEHCH causes dose-dependent accumulation of α2u-globulin in the kidneys of male Han Wistar rats, but has overall general safety. | |||||||||||||||||||||
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References
- [1]. Kang J, et al. Diethyl-hexyl-cyclohexane (Eco-DEHCH) is a safer phthalate alternative that does not elicit neuroendocrine disrupting effects. Journal of hazardous materials. 2025 Jul 05;491:137947. [Content Brief]
- [2]. Lee JY, et al. Evaluation of the 52-week chronic toxicity of a novel phthalate-free plasticizer, Eco-DEHCH (bis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate), in Han Wistar rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Jun;176:113809. [Content Brief]
